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“What About Bob” Vs. “A Beautiful Mind”

Examination Paper Watching these two motion pictures, â€Å"What about Bob? † And â€Å"A Beautiful Mind† truly make...

Tuesday, November 26, 2019

How To Make a Dry Ice Balloon

How To Make a Dry Ice Balloon You usually blow up balloons with air or helium, but did you know you can get a balloon to inflate itself using dry ice? Heres how you perform this simple science project: Dry Ice Balloon Materials BalloonsDry Ice PelletsFunnel (optional) Its easiest to work with a funnel because it holds the neck of the balloon open. If you are working with dry ice pellets, you may find it easier to break or crush them so you can pour them into the balloon. However, if you wear gloves, its pretty simple to do this project with just your hands and a balloon. If you have a carbon dioxide fire extinguisher, you can even make the dry ice yourself. What You Do Hold open the mouth of the balloon.Place or pour dry ice into the balloon.Tie off the balloon so that the gas wont escape.The balloon will inflate as you watch. Youll see water freeze on the outside of the balloon where the dry ice is cooling the air across the surface of the latex. How much the balloon inflates depends on how much dry ice you added. A small amount of dry ice will slightly inflate the balloon, while a large amount ultimately will make it pop. How It Works Dry ice is the solid form of carbon dioxide. At normal atmospheric pressure, dry ice sublimates from a solid directly into a gas. As the gas warms, it expands. Carbon dioxide is more dense than air, so if you drop a dry ice balloon, it will fall to the ground rather than float like a helium balloon. Dry Ice Safety Dry ice is cold enough that it can give you frostbite after a very brief exposure. Its best to wear gloves for this project and to let the balloon inflate on a countertop and not in your hand. Also, dont eat the dry ice. Keep it away from children and pets.

Friday, November 22, 2019

Not Selling Pull Your Book Off the Shelf

Not Selling Pull Your Book Off the Shelf One of the great advantages of indie publishing is being in control of your book. Recently a reader contacted me, asking my opinion about publishers. He was republishing a book done in 2011 that had not done well, blaming it on the vanity press. As someone ever interested in deterring folks away from those entities, I took a look at the book in an effort to assist. The cover was the best part. Beautiful. But it declined from there. The writing was chock full of grammar issues. The writing wasnt fluid. It was a memoir of sorts and wrought with the word I. The blurb was minimal and likewise full of errors. The author had no website, but worse, had not taken advantage of the Author Central page on Amazon, a freebie that every author ought to have fleshed out. As much as I abhor vanity presses and their predatory nature, I saw where they had done just what was asked of them. This was all on the author. My suggestion? Pull the book. Take it down. It hadnt sold well, so there was about used book sales keeping it active in the BN and Amazon databases.   I told him: 1) Pull the book 2) Cancel dealings with that press 3) Rewrite the book 4) Get feedback from a critique group 5) Get feedback from an editor 6) Redesign the cover 7) Acquire new blurbs 8) Acquire testimonials from those who did like it 9) Study indie publishing 10) Hire someone to format the print and digital book (although I adore Joel Friedlanders book templates)   11) Get his own ISBNs, especially if he intends to write more books 12) Use CreateSpace for print on Amazon 13) Use IngramSpark for print on non-Amazon sites 14) Use Amazon KDP for ebook on Amazon 15) Use Draft2Digital for ebook on non-Amazon sites Dont worry, this author wont recognize himself here. I get a few of these every week, asking how to proceed after a vanity press deal has flopped. Im adamant about protecting peoples privacy, but I received enough questions on this topic to warrant this weeks editorial. If you think this is you, dont let it bug you. Trust me, you have ample companionship in this dilemma. Your job now is to learn from your failures and spin it into success. Thats why we fail in the first place: to take us a step closer to doing it well.

Thursday, November 21, 2019

A Reflective Analysis on the Assessment and Management for ankle Essay

A Reflective Analysis on the Assessment and Management for ankle injury - Essay Example The placement experience obtained through patient assessments and management resulted into a better nursing intervention based on the pre-existing nursing knowledge for the future improvements. According to National Institute for Clinical Excellence (2004), reviews ankle joint injuries management in healthcare facility as a nursing responsibility aimed restoring the physiological function of the a ankle joint after an accident or injury has occurred. For the future practice, the nurses should reflect on the clinical experiences, concepts and understandings during the ankle injury assessment and management an adaptive response of care. Therefore, for this reflective analysis, the GIBBS model of reflection is used serving as a turning point in of ankle injury and related risks conditions assessment and management reflective analysis. GIBBS model of reflective analysis is a model of choice since it links the trainee nurses to their nursing practice, supervisors and their patients providing a systematic reflective of all the procedures and processes that were conducted in my nursing practice. For confidentiality and privacy of my nursing training experience, the name of the client, health facility, and the location has been made anonymous based on the reflective analysis for nurses’ survival in the word (Richards & Edwards, 2012). Ankle sprains are the most common sporting and UCC injuries anatomically and physiologically occurring as the tearing of bone-bone ligaments connection that stabilizes the ankle joint. My mentor reminded me that, the ankle injury causes destabilization of the hinge joint formed by fi bula, tibia and the talus bones resulting in structural disarrangement, fractures and deformity of the bones and ligaments around the ankle joint. Through the department orientation I learned that, the risks factors for the ankle joint injuries in United Kingdom are

Tuesday, November 19, 2019

Terrorist organization research and report on Hizballah (Party of God) Paper

Terrorist organization and report on Hizballah (Party of God) - Research Paper Example Specifically, Hezbollah gained its reputation for their bloody battles against invading Israeli occupational forces, during which they employed guerrilla warfare and martyr-based attacks. The Hezbollah began in 1982 as a response to the Israeli invasion of Lebanon. As their name literally translates to â€Å"Party of God†, they had deep religious motivations for starting the organization, though their direct actions may have seemed more political initially. During this time, Lebanon was controlled by Shia politics that had risen since the country’s liberation from France in 1943 (Norton, 2009, 21). At the outset, Israeli forces were welcomed into Lebanon to assist in forcing the Palestinians out of the southern part of the nation. However, when the Palestinians were successfully removed from the area, and Israeli occupation forces refused to leave the country in the following months, the Hezbollah viewed their actions as a direct threat to the Muslim way of life, as well as, an infringement on the Lebanese people independence. The founding members of Hezbollah were offended by the way the Israelis took ownership of their land. They were also not happy a bout the economic oppression the Israelis imposed on the native Shiites. Furthermore, the Hezbollah believed that these offenses required swift and violent action. This initiated the conflict between the nascent group and the Israeli forces, followed quickly by the involvement of other countries. To this end, in the first few years of the group’s infancy, the Hezbollah released a manifesto listing their objectives as the removal of Israeli occupation forces from Lebanon and the overall obliteration of Israeli forces from all nations. In this manifesto, they also described their desire to be free from all Western political or military involvement, as well. They viewed most of the Western nations as being allies to the Zionist movement (Jaber, 1997,

Thursday, November 14, 2019

Essay --

Zachariah Stottlemyre Prof. Steve Moore Eng. 101 10/27/2013 San Diego Comic-Con. Is it worth it? The San Diego Comic-Con is one of the largest events in the California bay area. Over 130,000 people attended this event last year alone. People all over the United states travel to visit this one week long event. Many come to showcase their skill as artists in many genres, hoping to find dream jobs, and to return next year as a booth vendor. Many people come hoping to spend hard earned dollars on comic books, movie paraphernalia, and much more. Many even blow all vacation days on this. If you love comics, movies, or even video games, then this event has a lot to offer you. Many have the opportunity to meet an actor, or talk to them in a discussion board, or even the chance to meet a creator of one of their favorite comics, and possibly find the purchase of a life time. When many first hear about Comic-Con all they think about is a bunch of nerds piling up in a gym to look at comic books and argue about who is better DC or Marvel. Many are partial to one or the other, so it was surely a fight for the ages. Then as the event began to take off and become more mainstream people began to take notice that is so much more than a compilation of comic books and nerds. Now it is an international event that draws people from all across the entire world. To begin with the event is in fact held in the San Diego Convention Center which has approximately 1,378,803 sq ft to host vendors, ticketing, panel conversations, etc. This leaving such a large opportunity to view several different booths, panels, and other exciting sites without too much over crowding and constant up in your face conversations. This alone makes the event worth spending ... ...e having enjoyed yourself, you must not of attended. Works Cited San Diego Convention Center. http://www.visitsandiego.com/exhibitors/buildingoverview.cfm Alex Suskind. Batman and Superman Movie Confirmed at Comic-Con 2013. http://news.moviefone.com/2013/07/20/batman-and-superman-movie-confirmed-at-comic-con-2013/ IGN. Big Movies at Comic Con 2013 List. http://www.ign.com/wikis/sdcc-comic-con/Big_Movies_at_Comic_Con_2013_List San Diego Comic Con International. http://www.comic-con.org/cci/2013/exhibitors San Diego Comic Con Interational. http://www.comic-con.org/cci/2013/childrens-film-festival San Diego Comic-Con 2013 Cosplay Wrap-Up. http://www.dorkly.com/article/53082/san-diego-comic-con-2013-cosplay-wrap-up Noelene Clark. Los Angeles Times. http://herocomplex.latimes.com/fans/comic-con-cosplay-costumed-role-players-become-temporary-superstars/#/0

Tuesday, November 12, 2019

Nature vs. Nuture

An Overarching View of Nature vs. Nature Katonia H. Dunaway Coppin State University Nature vs. Nurture 2 You got your brown eyes from your mother and your height from your father. But where did you get your thrill seeking personality and your talent for basketball. Did you get your eyes from your mom and your natural skill from your dad, or was it predetermined by your genes? Nature vs. Nurture 3The nature versus nurture debate is one of the oldest issues in psychology. The debate centers on the relative contributions of genetic inheritance and environmental factors to human development. Some philosophers such as Plato and Descartes suggested that certain things are inborn, or that they simply occur naturally regardless of environmental influences. Other well-known thinkers such as John Locke believed in what is known as tabula rosa, which suggests that the mind begins as a blank slate (2). According to this notion, everything that we are and all of our knowledge is determined by o ur experience.For example, when a person achieves tremendous academic success, did they do so because they are genetically predisposed to be successful, or is it a result of an enriched environment (2). Today, the majority of experts believe that behavior and development are influence by both nature and nurture. However, the issue still rages on in many areas, such as in the debate on the origins of homosexuality and influences on intelligence. Nature vs. Nurture 4 Nature- Heredity Scientists have known for years that traits such as eye color and hair color are determined by specific genes encoded in each human cell.The Nature Theory takes things a step further to say that more abstract traits such as intelligence, personality, aggression, and sexual orientation are also encoded in an individual's DNA(4). While it's clear that physical characteristics are hereditary, the genetic waters get a bit murkier when it comes to an individual's behavior, intelligence, and personality. Ultima tely, the old argument of nature vs. nurture has never really been won. We do not yet know how much of what we are is determined by our DNA and how much by our life experience.But we do know that ultimately both play a part. It has been reported that the use of the terms â€Å"nature† and â€Å"nurture† as a convenient catch-phrase for the roles of heredity and environment in human development can be traced back to the 13th century France (1). Scientists think that people behave as they do according to genetic predispositions or even â€Å"animal instincts. † This is known as the â€Å"nature† theory of human behavior (5). Other scientists believe that people think and behave in certain ways because they are taught to do so.This is known as the â€Å"nurture† theory of human behavior (5). Nature vs. Nurture 5 Fast-growing understanding of the human genome has recently made it clear that both sides are partly right. Nature endows us with inborn abi lities and traits; nurture takes these genetic tendencies and molds them as we learn and mature. But that’s not all. The â€Å"nature vs. nurture† debate still rages on, as scientist fight over how much of whom we are is shaped by genes. Nurture – EnvironmentWhile not discounting that genetic tendencies may exist, supporters of the nurture theory believe they ultimately don't matter and that our behavioral aspects originate only from the environmental factors of our upbringing. Studies on infant and child temperament have revealed the most crucial evidence for nurture theories and how much by the environment (6). American psychologist John Watson, best known for his controversial experiments with a young orphan named Albert, demonstrated that the acquisition of a phobia could be explained by classical conditioning.A strong proponent of environmental learning, he said: Give me a dozen healthy infants, well-formed, and my own specified world to bring them up in an d I'll guarantee to take any one at random and train him to become any type of specialist I might select†¦ regardless of his talents, penchants, tendencies, abilities, vocations and race of his ancestors(3). Nature vs. Nurture 6 Harvard psychologist B. F. Skinner's early experiments produced pigeons that could dance, do figure eights, and play tennis.Today known as the father of behavioral science, he eventually went on to prove that human behavior could be conditioned in much the same way as animals (4). If environment didn't play a part in determining an individual's traits and behaviors, then identical twins should, theoretically, be exactly the same in all respects, even if reared apart. But a number of studies show that they are never exactly alike, even though they are remarkably similar in most respects (1). So, was the way we behave engrained in us before we were born? Or has it developed over time in response to our experiences?Researchers on all sides of the nature v s. nurture debate agree that the link between a gene and a behavior is not the same as cause and effect. While a gene may increase the likelihood that you'll behave in a particular way, it does not make people do things. This in turn means that we still get to choose who we'll be when we grow up and the argument of nature vs. nurture continues to have theorist explore the question. References 1. Fierro, Pamela. Identical or Fraternal? You Can’t Always Tell by Looking Retrieved from http://www. about. com Guide. 2. Howe, M.J. A. (1997). IQ in Question: The truth about intelligence. London: Sage. 3. Hughes, Neiman. Nature vs. Nurture Ended. Retrieved from http://www. HumanNurtureome. org. 4. Johnson, Ramon. Nature versus Nurture. Newsletter, (2008, November 2) Pages 1-4. Retrieved February 28, 2010 from http://www. about. com. Guide. 5. Murray, Ralph. Nature vs. Nature Intelligence. Retrieved from http://www. wilderdom. com. 6. Powell, Kimberly. (2004, September 28). Are We Rea lly Born That Way? Retrieved February 28, 2010 from http://www. docstoc. com.

Saturday, November 9, 2019

Business Past Paper Essay

E of the following topics and write it in the space provided. (i) ‘The changing role of women in the family’ (ii) ‘The involvement of young people in organized sports’ Topic:_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 1. (a) State TWO reasons why a researcher would research the topic which you have stated above. (2 marks) (b) Suggest ONE objective on which a researcher may focus in doing a study on the topic you chose. (2 marks) (c) Based on the objective you suggested in 1 (b), write ONE research question. (2 marks) (d) State ONE appropriate method that may be used to collect data on the topic you chose. (1 mark) (e) Outline why a researcher should use the method you stated in 1 (d) above. (2 marks) Total 9 marks 2. (a) For the topic you have chosen, suggest TWO variables which a researcher may investigate. (2 marks) (b) Identify TWO groups from which a researcher may select a sample to get information on the topic you chose. (2 marks) (c) State ONE method of choosing a sample from ONE of the groups you identified in 2 (b) above. (1 mark) (d) Briefly describe the method you suggested in 2 (c). (2 marks) Total 7 marks 3. (a) Suggest TWO ways to display the data that may be collected on the topic you choose. (2 marks) (b) Explain briefly why the data should be displayed in the ways you suggested in 3 (a). (2 marks) (c) Name TWO statistical measures that a researcher may use to determine how numerical data, such as scores obtained in a study, are related. (2 marks) Total 6 marks Use the information in the passage below to answer questions 4 and 5. ALCOHOL AND FAMILY LIFE In a recent study done on the effects of alcohol on family life, the heads of fifty (50) low income households responded. The following information was obtained and analyzed. 30% of the respondents stated that alcohol consumption deprives some families from satisfying their basic needs, 60% indicated that it is a cause for domestic violence in the home while 10% claimed that it prevented family members from enjoying planned leisure activities. These findings have caused concern for many community groups. Leaders of these groups have indicated their desire to find some solutions to these concerns from the local authorities in their communities. 4. (a) (i) Display the findings obtained in this survey in a pie-graph in the space provided below. (4 marks) (ii) Write ONE statement about the data you displayed in the pie-graph. (2 marks) (b) State ONE characteristic of the sample used in this survey. (1 mark) (c) Name ONE research method that the researcher may have used to collect information. (1 mark) (d) Write ONE question that may be included in the research method you named in 4 (c). (1 mark) Total 9 marks 5. (a) Based on the data provided in the survey, write ONE research question. (2 marks) (b) Based on the findings you displayed in 4 (a) (i), suggest ONE recommendation that may be helpful to the community leaders. (1 mark) (c) State ONE change you would make if you were asked to conduct the study. (1 mark) Total 4 marks

Thursday, November 7, 2019

Intangible Assets in Finances

Intangible Assets in Finances Intangible assets are those assets that cannot be seen, in the past it has been difficult to value them since they lacked production cost and their value was not quantifiable. Either way, these assets are ever present in the many organizations, both profit making and non profit making.Advertising We will write a custom essay sample on Intangible Assets in Finances specifically for you for only $16.05 $11/page Learn More It is crucial for intangible assets to be measured since they play a major role in a firm’s aggressive sustainability. Also, some scholars believe that these assets are the backbone for a company’s growth. That being the case, there is a challenge of valuing them. Companies like CPA/ABVs have been created to specifically measure intangible assets. Examples of these assets include trademarks and copyrights (King Wiley, 2006). There are about four ways of measuring intangible assets, but the one that is commonly used is the disco unted cash flow method. In this method, intangible assets are valued according to how much money these assets will generate when put in use. This value should include taxes arising from the implementation of the asset, the risks involved, the cost of acquiring the assets, roles played by auxiliary intangible and tangible assets and finally the discount fee. This method is particularly used to measure the value of assets like expertise, computer programmes and franchises. The reason why this method is popular is because it does not require volumes of paper work to figure out the value and also it does not require highly skilled accountants to compute. Also, judging from other methods, this one appears to be more accurate and more focused on the future (King Wiley, 2006). However, since valuing of intangible assets is subjected to biasness, it is of at most important that more than one method be used. Using more than one method will lead to a more believable and a convincing value. T o give an example, the avoided cost method takes into consideration of what the value of an asset might have been in the past, but it does not include what its value will be in the future. To do that you will need to use the discounted cash flow method (Reilly Schweihs, 2004). The importance of valuing of intangible assets has been rapidly realized by companies all over the world. This is because the methodologies applied can be used to calculate the historical advancement value, potential value in the future and the economic value on tangible goods. Also, it justifies companies to charge consumers the cost arising from using intangible assets (Reilly Schweihs, 2004). Due to the application of methods of measuring intangible assets, it has brought some changes in the way trade is carried out. At the moment, intangible assets are recognized from a consumer’s viewpoint. Nevertheless, in the recent times, the viewpoint has changed from a consumer’s viewpoint to that of a market accomplice.Advertising Looking for essay on social sciences? Let's see if we can help you! Get your first paper with 15% OFF Learn More This means that the consumer will have to appreciate the cost arising from using various goods and services. This is irrespective of whether the consumer intends to use the intangible asset or not. It also means that consumers will have to pay for intangible assets which were once regarded as of having no value. In the end, consumers will be able to see charges of intangible assets in their pay slips and receipts (King Wiley, 2006). Even though this paper has been written by an accountant to another accountant, it is important that the general public reads it. By reading this paper, they will come to understand some of the charges that are imposed on them when they buy various goods and services. References King, A., Wiley, J. ( 2006). Fair Value for Financial Reporting: Meeting the New FASB Requirements. New Jerse y: McGraw-Hill. Reilly, R., Schweihs, R. (2004). Handbook of Business Valuation and Intellectual Property Analysis. New York: McGraw-Hill.

Tuesday, November 5, 2019

Chronological List of African Independence

Chronological List of African Independence Most nations in Africa were colonized by European states in the early modern era, including a burst of colonization in the Scramble for Africa from 1880 to 1900. But this condition was reversed over the course of the next century by independence movements. Here are the dates of independence for African nations. Country Independence Date Prior ruling country Liberia, Republic of July 26, 1847 - South Africa, Republic of May 31, 1910 Britain Egypt, Arab Republic of Feb. 28, 1922 Britain Ethiopia, People's Democratic Republic of May 5, 1941 Italy Libya (Socialist People's Libyan Arab Jamahiriya) Dec. 24, 1951 Britain Sudan, Democratic Republic of Jan. 1, 1956 Britain/Egypt Morocco, Kingdom of March 2, 1956 France Tunisia, Republic of March 20, 1956 France Morocco (Spanish Northern Zone, Marruecos) April 7, 1956 Spain Morocco (International Zone, Tangiers) Oct. 29, 1956 - Ghana, Republic of March 6, 1957 Britain Morocco (Spanish Southern Zone, Marruecos) April 27, 1958 Spain Guinea, Republic of Oct. 2, 1958 France Cameroon, Republic of Jan. 1 1960 France Senegal, Republic of April 4, 1960 France Togo, Republic of April 27, 1960 France Mali, Republic of Sept. 22, 1960 France Madagascar, Democratic Republic of June 26, 1960 France Congo (Kinshasa), Democratic Republic of the June 30, 1960 Belgium Somalia, Democratic Republic of July 1, 1960 Britain Benin, Republic of Aug. 1, 1960 France Niger, Republic of Aug. 3, 1960 France Burkina Faso, Popular Democratic Republic of Aug. 5, 1960 France Cà ´te d'Ivoire, Republic of (Ivory Coast) Aug. 7, 1960 France Chad, Republic of Aug. 11, 1960 France Central African Republic Aug. 13, 1960 France Congo (Brazzaville), Republic of the Aug. 15, 1960 France Gabon, Republic of Aug. 16, 1960 France Nigeria, Federal Republic of Oct. 1, 1960 Britain Mauritania, Islamic Republic of Nov. 28, 1960 France Sierra Leone, Republic of Apr. 27, 1961 Britain Nigeria (British Cameroon North) June 1, 1961 Britain Cameroon(British Cameroon South) Oct. 1, 1961 Britain Tanzania, United Republic of Dec. 9, 1961 Britain Burundi, Republic of July 1, 1962 Belgium Rwanda, Republic of July 1, 1962 Belgium Algeria, Democratic and Popular Republic of July 3, 1962 France Uganda, Republic of Oct. 9, 1962 Britain Kenya, Republic of Dec. 12, 1963 Britain Malawi, Republic of July 6, 1964 Britain Zambia, Republic of Oct. 24, 1964 Britain Gambia, Republic of The Feb. 18, 1965 Britain Botswana, Republic of Sept. 30, 1966 Britain Lesotho, Kingdom of Oct. 4, 1966 Britain Mauritius, State of March 12, 1968 Britain Swaziland, Kingdom of Sept. 6, 1968 Britain Equatorial Guinea, Republic of Oct. 12, 1968 Spain Morocco (Ifni) June 30, 1969 Spain Guinea-Bissau, Republic of Sept. 24, 1973(alt. Sept. 10, 1974) Portugal Mozambique, Republic of June 25. 1975 Portugal Cape Verde, Republic of July 5, 1975 Portugal Comoros, Federal Islamic Republic of the July 6, 1975 France So Tomà © and Principe, Democratic Republic of July 12, 1975 Portugal Angola, People's Republic of Nov. 11, 1975 Portugal Western Sahara Feb. 28, 1976 Spain Seychelles, Republic of June 29, 1976 Britain Djibouti, Republic of June 27, 1977 France Zimbabwe, Republic of April 18, 1980 Britain Namibia, Republic of March 21, 1990 South Africa Eritrea, State of May 24, 1993 Ethiopia Notes: Ethiopia  is usually considered to have never been colonized, but following the invasion by Italy in 1935-36 Italian settlers arrived. Emperor Haile Selassie was deposed and went into exile in the UK. He regained his throne on 5 May 1941 when he re-entered Addis Ababa with his troops. Italian resistance was not completely overcome until 27th November 1941.Guinea-Bissau  made a Unilateral Declaration of Independence on Sept. 24, 1973, now considered as Independence Day. However, independence was only recognized by Portugal on 10 September 1974 as a result of the Algiers Accord of Aug. 26, 1974.Western Sahara  was immediately seized by Morocco, a move contested by Polisario (Popular Front for the Liberation of the Saguia el Hamra and Rio del Oro).

Sunday, November 3, 2019

Highly Active Antiretroviral Therapy Essay Example | Topics and Well Written Essays - 1250 words

Highly Active Antiretroviral Therapy - Essay Example with undetectable HIV RNA levels, elective Caesarean section was associated with a 90% reduction in MTCT risk (odds ratio, 0.10; 95% CI, 0.030.33), compared with vaginal delivery or emergency Caesarean section. Conclusions.The results suggest that offering an elective Caesarean section delivery to all HIV-infected women, even in areas where HAART is available, is appropriate clinical management, especially for persons with detectable viral loads. Our results also suggest that previously identified risk factors remain important. (Source : European Collaborative Study). Several currently available drugs are under further development, the most important goals being the reduction of pill burden, easier dosing and less side effects. Three such preparations to have recently entered the market are Invirase 500, Truvada and Kivexa. New improvements are being developed; licensing applications for some of these are already in progress. Gilead and BMS are working on a combination pill of FTC, tenofovir and efavirenz. However, it will be some time before this so far one-off co-operation bears fruit. With increasing numbers of HIV-infected pregnant women receiving highly active antiretroviral therapy (HAART),1 concerns have been raised over the possible teratogenic effects related to exposure in early pregnancy. It has been reported that a .4% prevalence of congenital abnormalities in uninfected infants exposed to antiretroviral therapy (ART; mainly monotherapy and/or dual therapy), which is similar to that seen in those not exposed. It has not been proven that whether risk of congenital abnormalities is increased by first-trimester exposure or by use of HAART, but there is an additional risk of antenatal use of HAART during...N Engl J Med 1996, 335:1081-90. 16. Mocroft A, Katlama C, Johnson AM, et al. AIDS across Europe, 1994-98: the EuroSIDA study. Lancet 2000, 356:291-6. Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 1996, 271:1582-6. 18. Volberding PA, Lagakos SW, Koch MA, et al. Zidovudine in asymptomatic HIV infection. A controlled trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. N Engl J Med 1990, 322:941-9.